Substance Use Treatment Centers
Content added Oct. 24, 2025
We are a network of faith-based, peer and community organizations committed to restoring the lives of families affected by substance use disorders. We aim to provide immediate access to resources and build long-term relationships for sustained recovery.
Phone: 573-761-1087
Content updated March 18, 2026
Search for Missouri Alcohol and Drug Rehab Center (2024) Missouri residents have several options for addiction treatment centers. This list highlights facilities that offer recovery programs.
Valley Hope of Boonville, Missouri provides compassionate, patient-centered care supported by evidence-based therapies as well as clinical and medical experts.
1415 Ashley Rd
Boonville, MO 65233
660-882-6547
Women Only
Content updated Nov. 6, 2023
As Medical Professionals and Peers we are able to provide all modalities of Addiction Treatment including all forms of Medication Assisted Treatment (MAT) along with Cognitive Behavioral Therapy , Peer Support, 12 step Meetings and Group Therapy. Housing & Treatment Under the Same Roof.
Hours: Monday – Friday, 9:00 am – 5:00 pm
501 Fifth Street
Columbia, MO 65201
816-808-2233
Adults and Youth
Content updated Oct. 13, 2023
67 locations with services that include those with developmental disabilities, children in foster care, those seeking employment, individuals impacted by a mental illness, substance use disorder, or domestic violence, or those individuals who are deaf or hard of hearing, are on the autism spectrum, or have been impacted by a brain injury.
Content updated Oct. 13, 2023
This service is intended to help medically treat adults who are experiencing withdrawal issues from drugs and alcohol, so that they can begin their path to recovery. In-patient stay includes pre-screening, assessment, admission, medical stabilization and appropriate discharge planning. Accept Medicaid, Medicare and private insurance, and can also work with individuals needing to arrange for self-pay. Patients can self-refer by calling for a screening Mon - Fri, 8 AM - 5 PM.
1125 Madison St
Jefferson City, MO 65102
573-632-5817 800-939-2273
Mark Twain Behavioral Health (MTBH) is a private not-for-profit Certified Community Behavioral Health Clinic (CCBHC) serving our community of Northeast Missouri since 1975. In July 2021, Turning Point Recovery Centers joined our team. This addition has allowed us to broaden our array of services and increased our community footprint. MTBH provides a wide range of services for youth, adults, couples, and families.
Locations:
154 Forrest Drive
Hannibal, MO 63401
573-221-2120
105 Pfeiffer Avenue
Kirksville, MO 63501
660-665-4612
309 N. Missouri Street
Macon, MO 63552
660-395-9114
Content updated Feb. 9, 2024
Substance Use Disorder
Adult Outpatient Treatment Services
Adult Partial Hospitalization Treatment Services
Adult Residential Treatment Services
Adult Co-occurring Treatment Services
Medication Assisted Treatment (MAT) Services
Substance Awareness Traffic Offender Program (SATOP)
1091 Midway Drive
Linn Creek, MO 65052
844-853-8937
Adults with severe and persistent mental health issues and some have co-occurring substance use disorders. We accept Medicaid and Medicaid/Medicare. Also homeless in Boone County who have a mental illness.
Content updated April 3, 2026
New Horizons is a not-for-profit community mental health center, providing specialized Community Psychiatric Rehabilitation Program (CPRP) services to adults with severe and persistent behavioral health issues in Cole County and Boone County, Missouri. We also have a homeless outreach program in Boone County.
Services include:
Community Psychiatric Rehabilitation Program- Adult Psychiatric Services
Initial/ Annual Evaluation and Treatment Plan
Medication Services
Integrated Treatment for Co-Occurring Disorders
Healthcare Home
Psychosocial Rehabilitation Centers (PSRCs)
Residential Services for CPRP eligible consumers in Jefferson City and Columbia
Melody House Residential Care Facility- Jefferson City
Harambee House Residential Care Facility- Columbia
PATH Homeless Services- Boone County
Hours: M-F, 8am-4:30pm
Email: InfoRequest@mo-newhorizons.com
1408 Hathman Place
Columbia, MO 65201
(573) 443-0405
2013 Williams St
Jefferson City, MO 65109
(573) 636-8108
Content updated Dec. 4, 2023
Services Offered - Behavioral Health Services including:
• Therapy for Adults
• Psychiatry for Adults
• Substance Use Disorder Outpatient Treatment for Adults and Adolescents (NAVIG8 adolescent program located upstairs)
• Substance Awareness Traffic Offender Program (SATOP)
Open Access: To be connected with behavioral health services at Compass Health, you can walk-in to the Berrywood Clinic anytime Mon-Fri 8 AM- 4 PM for an initial assessment (entrance located in the back of the building). This is a thorough intake process and can take up to an hour.
NAVIG8 Adolescent Treatment Program: outpatient program for adolescents and families whose lives have been impacted by the use of alcohol and/or other substances. The program serves adolescents ages 9 through 17 and is structured to meet the specific needs of each person and his or her family. The entrance is located in the front of the building.
3501 Berrywood Drive
Columbia, MO 65201
844-853-8937
Brochure of Compass Health Network Central Region Locations
Women 18+ and their children ages 12 and under
Content updated Dec. 1, 2023
McCambridge welcomes women ages 18 and older who are living with a substance use disorder; offering an array of comprehensive services on a residential and outpatient basis, including:
- An RN on staff to assist with a gender specific need, including pregnancy;
- Parenting classes;
- Family/child-centered services;
- Medically assisted treatment.
Inpatient programming is provided in a safe, comfortable, and health environment.
200 Portland Street
Columbia, MO 65201
To schedule an appointment: 844-853-8937
Adults and Youth
Outpatient, assessment and diagnosis, adult and youth counseling, relapse prevention. Self-payment.
219 N 9th Street
Columbia, MO 65201
573-441-0120
Adults Only
Content updated Nov. 14, 2023
Long term Opioid Maintenance treatment. Methadone and Suboxone maintenance treatment. Narcan available. Medicaid and Medicare, private Insurance, and self-payment. Intakes are usually Monday through Friday at 6:30am and will need two forms of valid ID.
1301 Vandiver Drive, Ste Y
Columbia, MO 65202
573-449-8338
Youth Only, ages 13-25
Content updated March 20, 2026
PHP, IOP, OP and support group meetings for parents and young adults with weekend activities.
Hours: 11-5, M-F
626 Cepi Drive
Chesterfield, MO 63005
(636) 532-9991
Email: info@thecrossroadsprogram.com
Content updated Jan. 17, 2024
Children and Adolescents
CenterPointe Hospital of Columbia provides mental health and addiction treatment services for adolescents (12-17), adults and senior adults. They provide a wide range of behavioral healthcare services – including acute inpatient, intensive outpatient, detoxification and medication assisted treatment – to youth, adults, and seniors.
1201 International Dr
Columbia, MO 65202
855-623-7016
Content updated Oct. 24,, 2025
Multiple locations serving underserved populations
Burrell Behavioral Health is a mental health resource that is located throughout the state of Missouri.
Locations:
Outpatient therapy, psychiatry, pharmacy services: 3401 Berrywood Dr Columbia 65201, 8 am - 5 pm;
Primary care and behavioral health crisis center: 1805 E Walnut St, Columbia, MO 65201, Primary care - 8 am - 5 pm; Crisis Center 24 hours, 7 days a week, 365 days a year;
Substance use disorder clinic: 90 E Leslie Ln Columbia 65201, 8 am - 5 pm;
Intensive Residential Treatment Services (IRTS): 1611 Towne Dr Columbia 65202, 8 am - 5 pm.
Phone: (573) 777-8300
Burrell at a Glance Flyer
Burrell Behavioral Health | Home (burrellcenter.com)
Content updated Oct. 13, 2023
SAMHSA’s National Helpline is a free, confidential, 24/7, 365-day-a-year treatment referral and information service (in English and Spanish) for individuals and families facing mental and/or substance use disorders.
Also visit the online treatment locator.
Sober Living
Content updated April 30, 2024
Provides treatment for those seeking recovery from drug and alcohol addiction. Visit website for office hours and clinic hours.
90 E Leslie Ln
Columbia, MO 65202
573-615-1466