Missouri Secretary of State – Business Services
600 West Main Street Jefferson City, MO 65101 573-751-4936
Missouri Small Business Development Center
Lafferre Hall 416 S 6th St. Room E2437N Columbia, MO 65211 573-884-8087
Free online course and guidance addressing topics such as management, marketing and strategic planning is available for new and existing businesses. All one-on-one counseling is confidential.
Missouri Innovation Center
1601 S Providence Rd Columbia, MO 65211-3460 573-884-0496
Provides unparalleled entrepreneurial support centered in Columbia, Missouri, and offers a wide range of services. They offer state-of-the-art facilities, mentoring, access to world-class university research facilities and financing possibilities.
Missouri Department of Economic Development
301 W High St Jefferson City, MO 65101 573-751-4962
ded.mo.gov/business/start-up-entrepreneurship-programs
Resources for Missouri's Startups & Small Businesses
Minority Business Development Agency
1401 Constitution Ave NW Washington, DC 20230
A division of the U.S. Department of Commerce. Creating Pathways to Economic Empowerment. The vision of MBDA's Enterprising Women of Color initiative is to connect women entrepreneurs to a community of wealth-building resources. Grow your network, expand your client base, and connect to entrepreneurial ecosystems.
Federal Tax Centers for Small Business/Self-Employed
www.irs.gov/businesses/small-businesses-self-employed/tax-centers
This site provides a list of tax centers that have been developed to help you quickly find information related to your particular area of interest, industry or profession on one page.
Enterprise Development Corporation
910 E Broadway, Ste 201 Columbia, MO 65201 573-875-8117
Provider for the Small Business Administration 504 Loan Program.
Columbia Regional Economic Development, Inc. - REDI
500 E Walnut St, Ste 102 Columbia, MO 65201 573-442-8303
www.columbiaredi.com/programs/grow
REDI supports local businesses and the creativity and innovation of entrepreneurs through events and programming that foster a strong entrepreneurial ecosystem.
Columbia Chamber of Commerce
300 S Providence Rd. Columbia, MO 65201 573-874-1132
Be part of moving you and your business forward by joining more than 1,000 other members of the Columbia Chamber of Commerce.
City of Columbia - Minority & Women Owned Business Directory
500 E Walnut, Ste 102 Columbia, MO 65201 573-441-5544
City of Columbia - Business License Division
701 E Broadway, 5th Floor PO Box 6015 Columbia, MO 65201 573-874-CITY (2489)
Cre8
A one-stop shop of resources for a diverse range of makers with a shared branding program, a community-wide awareness campaign, an online makers directory, educational workshops, regular maker meet-ups, pop ups and tasting events, and assistance locating manufacturing space along The Loop corridor.
cre8como.com
Uplift Mid-MO
Content updated Aug. 9, 2024
222 S Jefferson St., Suite 305 (basement level)
Mexico, MO 65265
573-212-8376
Visit website
Handi-Shop
Meaningful employment opportunities for people with disabilities in a safe, supportive, and productive environment
508 East Liberty
Mexico, MO 65265
573-581-1191
Martin Keller, Manager, hsimanager@handi-shop.com
Teresa Shaw, Office Administrator, hsioffice@handi-shop.com
Vocational Rehabilitation Jefferson City
Content updated Aug. 5, 2024
Find assistance and training for those who would like to work but have a disability that keeps them from finding or keeping a job.
205 Jefferson St.
Jefferson City, MO 65101
573-751-2343
Email: info@vr.dese.mo.gov
Mexico Housing Authority
Manage a total of 203 Public Housing units in the style of duplex apartments with units of ADA compliance and a total of 151 Housing Choice Vouchers (formerly Section 8). These two programs are provided for low-income families through the funds of Housing and Urban Development.
828 Garfield Ave
Mexico, MO 65265
573-581-2294
CMCA Mexico
Content updated July 17, 2026
CMCA supports low-income individuals and families. When a family comes to us with a specific need, we use a whole family approach and work with these families to provide support for any additional needs by referring them to other programs offered.
801 E Breckenridge
Mexico, MO 65265
573-582-7864
Audrain County Help Center
Content updated Aug. 9, 2024
Food Pantry and Thrift Store We serve those who reside in Audrain County. We assist with Photo ID and Driver's License, Water and Sewer bills. RX assistance, Hygiene items.
409 Fairground St.
Mexico, MO 65265
Hours of operation: 9am-5pm
Food Pantry Hours
Mon-Noon-4pm
Wednesday-9am-1pm
Friday 2-5:30 pm
Email: executive.director@mexicohelpcenter.org